Vincenz-Hospital, Limburg, Germany The sentinel node concept SNC and the sentinel node procedure SNP is crucial to understand the relationship of the primary tumor to its regional lymphatics. The adjuvant radiotherapy to lymphatic basins indicated by the SNP could avoid a systematic lymphadenectomy in sentinel node positive patients.
- RADICAL RETROPUBIC PROSTATECTOMY – INITIAL EXPERIENCE | The Medical-Surgical Journal
- Prostate cryotherapy is successfully used in patients with prostate cancer, either as a primary treatment or second recourse after failure of radiotherapy.
- Thuja în tratamentul prostatitei
We will present here the concept of sentinel node navigation radiotherapy. Also we shall present data on the selection of lympatic areas to be included in the clinical target volume CTV in head and neck, breast, apparently localized prostate cancer and Merkell Cell carcinoma patients based on the pattern of lymphatic spread indicated by the SNP. Conformal irradiation techniques for adjuvant radiotherapy of the head and neck, axillary and internal mammary chain IMCinguinal and pelvic lymphatic areas are presented.
- Supozitoare cu longidază pentru prostatită
- Nowadays, most cases are detected and treated at an early stage, when the tumor is still localized within the prostate.
- Abstract Aim: To evaluate our experience with the first cases of radical retropubic prostatectomy and to use the results for patient counseling and optimizing therapeutic decision.
- Magnetic Resonance Imaging MRI is the best imaging modality for evaluating the prostate and accurately diagnose the prostatic carcinoma, especially in cases with aggressive and larger volume tumors.
Basic data on the lymphatic drainage and involvement of different lymph nodes for head and neck, breast, and prostate cancer as well as Merkel Cell carcinoma patients based on the SNP were used.
For treatment planning and CTV delineation the individual location of lymph nodes in axial CT slices was used. The data obtained using the SNP changed the criteria of selection of different lymphatic basins to be included in the CTV in a significant manner.
In Merkel Cell carcinoma patients the SNP is the only available method to describe the individual lymphatic basin and to adapt the optimal treatment strategy.
The conventional irradiation techniques for lymphatic areas in the axilla, IMC, groin and pelvis actually in după prostatita acută are not adequate and have side effects.
At our institution new conformal irradiation techniques for lymphatic areas or basins have been developed and are presented here. The concept of the sentinel node navigation radiotherapy and the individual selection of lymphatic areas to be included in the CTV based on the SNP were presented. Sparing of organs at risk and homogenous dose coverage of the CTV using the proposed irradiation techniques is possible.
Multiparametric Magnetic Resonance Imaging in prostate cancer diagnosis: a must
Methods: The crude, age-specific and directly age-standardized incidence and mortality rates for GU cancers in Romania were calculated. Time trend of the incidence and mortality was assessed by the percent change between and Results: Although in Romania, incidence and mortality rates of GU cancers are lower than in western countries, there was a general increase in the incidence and mortality during the registered period.
For urological cancers, the increase concerned both sexes, though incidence and mortality rates in women remained significantly lower than in men. Conclusions: Our data support that the application of available knowledge on prevention, diagnosis and treatment of these cancers could define a localized prostate cancer stage to reduce during the following years the impact of the ascending course of incidence and mortality through GU cancers in Romania.
Results: 32 patients received prior adjuvant treatment 5FU based in both groups, 7 stage II at diagnosis and 25 stage III at diagnosis; 41 patients from both groups received no prior chemotherapy stage IV disease before enrollment. Both regimens proved to be active; 4 Except for one death by myocardial infarction possibly related to Capecitabine therapy, toxicity was mild, with very few grade three events. Median follow-up was 12 months, range Median overall survival was Conclusion: Both regimens proved active in metastatic setting, with moderate toxicity and increased compliance from patients.
PrOstatE caNcEr: EPIDEMIOLOGY, EtIOLOGY, PathOLOGY, DIaGNOsIs, aND PrOGNOsIs | Semantic Scholar
Surgery was planned weeks after the completion of radiochemotherapy. The pathological specimen was evaluated for primary tumor, number of examined lymph nodes and resection margins.
The compliance and toxicity of the concomitant preoperative treatment, and complications after surgery were recorded. The pathological response rate pCR was complete in The grade 3 toxicity was mainly hematological No grade 4 toxicity was registered. Conclusions: Concomitent preoperative radiochemotherapy with Capecitabine in patients with locally advanced rectal adenocarcinoma has a strong rational support: efficacy, favorable safety profile and moderate toxicity.
The oral chemotherapy i. Key words: Colorectal Cancer, Adjuvant Treatment. Bisphosphonates BP represent an important method of their treatment. Purpose: to evaluate the efficiency and toxicity of different type of BP in terms of the incidence of skeletal events, the time to the first skeletal- related event and the incidence and severity of adverse effects.
The median age of the patients was 66 years. At least three cycles of BP were administered, half of them being with zoledronic acid. The median time until the first event was 17 months 22 for Zometa vs. None of the patients underwent bone surgery.
Severe localized prostate cancer stage resulted in osteonecrosis of the mandible 1case and kidney failure 1 case. The other adverse effects included arthralgia, myalgia, temporary exacerbation of bone pain and gastrointestinal adverse reactions.
Conclusions: Zoledronic acid seems to be more effective in treating bone metastases since it reduces the incidence of skeletal events and increases the time interval until the first skeletal related event, compared to Aredia or Clodronate. Key words: Bisphosphonates, Prostate Cancer. Its diagnosis is difficult and very often late because the lesion originates in the submucosa of the stomach wall endoscope biopsy is often inconclusive and also because of the unspecific clinical manifestations even with distant metastasis absence of carcinoid syndrome.
The proper therapeutic attitude includes removal of the tumour surgically or endoscopically along with complementary chemotherapy, depending on the carcinoid type, size of the lesion and disease stage. We hereby give our personal experience with regard to the problems of diagnostic and classification by the type of patients diagnosed with gastric malignant carcinoids in our survey.
Ai fost blocat(ă) temporar
This paper also presents particularities of surgical and complementary treatment and of the postoperative outcome.
Small molecule tyrosine kinase inhibitors may change the outlook in these patients. We present the case of a 62 year old female who was diagnosed in March with chronic phase, Philadelphia positive CML. She was initially treated with hydroxyurea with the achievement of a complete haematological response CHR but in July the patient progressed to blastic phase.
- Volum 14 Numarul 2, | Srrom
- Source: Acta Medica Transilvanica.
- Te poți simți amețit cu prostatita
Subsequently, the patient was started on dasatinib 2 x 70mg daily gaining the achievement of CHR after one month. Major cytogenetically remission was obtained in 3 months and complete cytogenetically remission CCR in 6 months.
Treatment options for early (localised) prostate cancer
This case report underscores the progress being made in localized prostate cancer stage years in the treatment of CML, even in advanced phases, due to the introduction of tyrosine kinase inhibitors.